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From the High Desert book cover

From the High Desert

A Cultural History of Art Bell

Thumbnail for December 11, 2002: Microbiology and Ethics - Jon Beckwith

December 11, 2002: Microbiology and Ethics - Jon Beckwith

Dec 11, 2002
2h 50m
0:00 / 0:00
Art Bell speaks with Harvard professor Jon Beckwith, a pioneering geneticist whose lab first isolated a pure gene from an organism in 1969. Beckwith discusses how he held a press conference to announce that achievement and simultaneously warn the public about the dangers of genetic manipulation. He reveals that colleagues at Harvard once attempted to have his tenure revoked for raising ethical objections to a controversial study screening newborn boys for the extra Y chromosome supposedly linked to criminal behavior.

The conversation centers on the announcement by J. Craig Venter and Hamilton O. Smith that they plan to create a new single-celled life form in a laboratory dish. Beckwith expresses skepticism about the hype, noting that Venter himself admitted scientists still understand very little despite completing the human genome. He cautions that while engineered organisms may cause harm, nature has already selected organisms to be as destructive as they can be, and genetically modified creations are unlikely to outperform natural pathogens long-term.

Art and Beckwith also examine human cloning, genetic privacy, and biological weapons research. Beckwith argues that defending against biological warfare inevitably involves developing offensive capabilities and warns that the pace of genetic discovery is outrunning society's ability to establish adequate privacy protections and ethical safeguards.

Key Moments

  1. Race-targeted bioweapons would be suicidal: Art asks whether a geneticist with Beckwith's knowledge could engineer a bioweapon targeting a specific race; Beckwith says shared DNA across populations would make any such weapon effectively suicidal.

  2. The XYY screening fight: Beckwith recounts his early-career fight against a Harvard-affiliated study screening newborn boys for XYY chromosomes, where parents would learn their child was being tracked as potentially predisposed to violence.

  3. The Pahrump genetic-testing van scenario: Art imagines a free genetic-testing van rolling into his town; Beckwith warns the resulting data would inevitably leak into insurance and employment records, the way HIV testing data did.

  4. Cloning: many monsters before a perfect human: On Severino Antinori's claimed pregnant cloned woman, Beckwith warns that current cloning technology will produce many failed and damaged outcomes long before any healthy cloned human is achieved.

  5. Reston's airborne Ebola moment: Art recalls a 60 Minutes piece on the Reston monkey outbreak where airborne transmission of an Ebola-related virus was confirmed, and asks Beckwith how close we are to that happening with humans.